Hepatoprotective Effect of Enicostemma littorale blume and Eclipta alba During Ethanol Induced Oxidative Stress in Albino Rats
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چکیده
منابع مشابه
Protective Effect of Enicostemma littorale Blume Methanolic Extract on Gentamicin-Induced Nephrotoxicity in Rats
Problem statement: The Amino glycoside antibiotics cause drug induced nephrotoxicity at therapeutic doses and thus limits the use clinically. Oxidative stress is one of the main reasons for the development of nephrotoxicity. Approach: In light of this the aim of the present study was to investigate the role of mitochondrial as well as post-mitochondrial oxidative stress in the development of Ge...
متن کاملHypoglycemic effect of aqueous extract of Enicostemma littorale Blume (chhota chirayata) on alloxan induced diabetes mellitus in rats.
The whole plant aqueous extract of E. littorale was tested for its hypoglycemic activity on normoglycemic, hyperglycemic and alloxan induced diabetic rats. Blood sugar lowering activity was not observed in normoglycemic and glucose loaded hyperglycemic rats in the short time experiment. But in case of diabetic rats, the fall of blood sugar after 30 days treatment with the aqueous extract was fo...
متن کاملEffect of Eclipta Alba on Fructose Induced Hypertension in Albino Rats
ObjectiveHypertension is a common disorder rising in incidence once established treatment is obligatory. The causes, so also the drugs are many & usually the treatment is lifelong. Hence research is going on to find out a suitable & safe drug. Herbal products in this regard are worthy of investigation. Eclipta alba Hassk (Bhringaraja) is recently reported to have diuretic & antihypertensive act...
متن کاملEvaluation of effect of aqueous extract of Enicostemma littorale Blume in streptozotocin-induced type 1 diabetic rats.
The present investigation was undertaken to standardize and study the dose-dependent effect of three weeks treatment with hot and cold aqueous extract of E. littorale (0.5, 1 and 2 g/kg, po) on streptozotocin (STZ) induced type I diabetic (confirmed by histopathology) rats (45 mg/kg, iv single dose). Treatment of rats with STZ produced cardinal signs of diabetes-mellitus like a significant loss...
متن کاملEnicostemma littorale Blume aqueous extract improves the antioxidant status in alloxan-induced diabetic rat tissues.
This study investigates the effect of oral administration of an aqueous Enicostemma littorale whole plant extract on antioxidant defense in alloxan-induced diabetes in rats. A significant increase in blood glucose and increased concentration of thiobarbituric acid reactive substances (TBARS) and hydroperoxides (HP) in liver, kidney and pancreas were observed in alloxan diabetic rats. Decreased ...
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ژورنال
عنوان ژورنال: International Journal of Pharmacology
سال: 2009
ISSN: 1811-7775
DOI: 10.3923/ijp.2009.268.272